Damien_Thorne (Stranger)
07-24-00 01:42
No 32463
      Psilocybin  Bookmark   

Call me dumb, but I was just wondering if there was a method out there which would enable me to synthecize psilocybin.  Mushrooms have always been among a favorite of my trips.

=>I am a firm believer in my Constitutional Right to the Pursuit of Happieness<=
(Chief Bee)
07-24-00 07:10
No 32556
      Re: Psilocybin  Bookmark   

These are probably the best methods available:


(Hive Bee)
07-25-00 13:12
No 32985
      Re: Psilocybin  Bookmark   

Why synthesize when you can just grow the darn things?

07-26-00 04:52
No 33313
      Re: Psilocybin  Bookmark   

Do you know what is the regioselective thallation of the 4-position and how to make it ?
I think that a good way could be attack directly DMT in 4 position and then make the acetoxy, in Psychedelic chemistry, Michael Valentine gives a rxn with H2O2 and Cu Sulfate (don't remember exactly) that yields a mixture of different OH DMT, taht can be separated with chromatography, what do you think about it ?
This regioselective thallation seem to be be better.

07-26-00 11:29
No 33434
      Re: Psilocybin  Bookmark   

Thallium? shocked It's extremely toxic and it's polluting the environment. Bad idea. Other 4-hydroxylation reactions have low yields or need many steps. You can find the literature references on my site: Lilienthals References (http://www.fortunecity.com/westwood/storey/116/).

(Hive Bee)
07-27-00 01:45
No 33753
      Re: Psilocybin  Bookmark   

Awww, but it's just not a trip unless your eyebrows fall out!!!


(Hive Bee)
07-27-00 02:31
No 33762
      (empty)  Bookmark   

(Hive Bee)
07-27-00 02:35
No 33763
      Re: Psilocybin  Bookmark   

Lilienthal, don't you know the hydroxylation in Psychedelic Chemistry ? a 30 % yield seems good.