oxygen ( )
09-03-98 20:13
No 99418
      antranyl acid from phtal.anhydr.?  Bookmark   

Here is industrial method for antranyl.acid:
phtal. anh.  + NH3(aq) -> phtalamin.acid
phtalamin. acid + NaOCl -> antranyl.acid
Is it useful for laboratory?


 
 
 
 
    Cheapskate
(Member)
09-04-98 03:07
No 99420
      Re: antranyl acid from phtal.anhydr.?  Bookmark   

I think Oxygen is talking about anthranilic acid.  One of my favorite precursors. 

Oxygen, would you post more details on this??

Please.

 
 
 
 
    Rhodium
(Administrator)
09-04-98 03:32
No 99421
      Re: antranyl acid from phtal.anhydr.?  Bookmark   

The reactions are already in my Quaalude FAQ. The only difference is that it uses OBr- instead of OCl- for the final reaction. Compare with the hofmann reaction in Eleusis Methylamine FAQ, and you have a complete OTC synth for anthranilic acid.

Could somebody help me work out the synthetic details for the NaOCl + phtalimide => anthranilic acid reaction? Cheapskate?

 
 
 
 
    Cheapskate
(Member)
09-25-98 03:55
No 99422
      Re: antranyl acid from phtal.anhydr.?  Bookmark   

Is phthalic anhydride OTC??? What is it used in.  I've looked around and haven't found it.  This sounds like an interesting reaction to pursue.
 
 
 
 
    Rhodium
(Administrator)
09-25-98 10:21
No 99423
      Re: antranyl acid from phtal.anhydr.?  Bookmark   

Naphtalene can be oxidized to phtalic acid with sulfuric acid with catalytic mercury sulfate. The anhydride forms on heating of the di-acid.

Are we making quaalude from earth, wind & fire yet? 

 
 
 
 
    Cheapskate
(Member)
09-25-98 22:16
No 99424
      Re: antranyl acid from phtal.anhydr.?  Bookmark   

I'm getting closer, I just finished working out the route using polyphosphoric acid and have found a way to maximize yield.  Using wind to evaporate, fire to heat, water to force crystalization, the earth part is hard.
 
 
 
 
    oxygen
( )
09-30-98 02:08
No 99425
      Re: antranyl acid from phtal.anhydr.?  Bookmark   

Graebe,Rostowzew, Ber._35_, 2747(1902)
with NaOCl -> _Yield=95%_
 
 
 
 
    Aurelius
(Hive Bee)
11-19-02 23:06
No 381317
      ?  Bookmark   

does anybody know about this?  viable?  (procedure maybe?)
 
 
 
 
    Rhodium
(Chief Bee)
11-20-02 00:11
No 381349
      Anthranilic Acid from phtalic anhydride  Bookmark   

As I said above, the procedure is already on my page, see the section Method 2: Anthranilic Acid from phtalic anhydride in the document at ../rhodium/chemistry /quaalude.html