The_Animal (Hive Addict)
08-06-01 18:00
No 201983
      1,2,4 Trimethoxybenzene  Bookmark   

1,2,4 Trimethoxybenzene:

Is this useful for anything apart from the (Too) long and involved TMA-4 (I think!,Lycaeum is down so can't check) synth in Pikhal or the purpose of wallpaper stripping in which I found it was the sole ingredient in som old backstreet DIY shop, normally in swims area its all DCM/MeOH or Xylene or Toluene so was quite surprised to findtongue

The all new fangled http://originalanimal.homestead.com
 
 
 
 
    Rhodium
(Chief Bee)
08-07-01 07:05
No 202155
      Re: 1,2,4 Trimethoxybenzene  Bookmark   

http://www.erowid.org/library/books_online/pihkal/pihkal161.shtml (for the tedious preparation of TMA-5)

Formylation of your trimethoxybenzene under vilsmeyer conditions would probably give a mixture of 2,3,6-trimethoxybenzaldehyde and 2,4,5-trimethoxybenzaldehyde.
 
 
 
 
    The_Animal
(Hive Addict)
08-07-01 15:40
No 202313
      Re: 1,2,4 Trimethoxybenzene  Bookmark   

Cheers chief!
Hmmn - I think I've seen a few avenues of exploration on the 2,4,5 positioning but can't recall seeing too many with 2,3,6. Will the temperature of the distillation vary with two compunds so similar? Or would I get an (un?)interesting 2,3,6 analogue?
So basically TMA something's is the pot of gold at the end of the rainbow. Are there any other possible synths for the chem-house challenged (Although not photographically challenged)  frown

The all new fangled http://originalanimal.homestead.com
 
 
 
 
    Rhodium
(Chief Bee)
08-07-01 16:27
No 202324
      Re: 1,2,4 Trimethoxybenzene  Bookmark   

I believe the benzaldehydes could be separated by distillation if you choose that route, but I also believe that the 2,4,5-isomer will predominate (Starting material for TMA-2).

What do you want to produce? "Anything from 1,2,4-trimethoxybenzene"?

 
 
 
 
    The_Animal
(Hive Addict)
08-08-01 01:14
No 202465
      Re: 1,2,4 Trimethoxybenzene  Bookmark   

Well, I was just checking the options. It's not very often I come across otc benzene that has possible naughty usestongue

The all new fangled http://originalanimal.homestead.com
 
 
 
 
    The_Animal
(Hive Addict)
08-22-01 06:08
No 206530
      Re: 1,2,4 Trimethoxybenzene  Bookmark   

Is there any other options other than  using DMF and POCl3. I need something a bit more <choke>OTC.

I'm gonna do some checking myself but alas I am swimming in new waters so to speak

The all new fangled http://originalanimal.homestead.com
 
 
 
 
    PolytheneSam
(Master Searcher)
08-24-01 17:11
No 207141
      Re: 1,2,4 Trimethoxybenzene  Bookmark   

This looks like an interesting possibility.
http://164.195.100.11/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=/netahtml/srchnum.htm&r=1&f=G&l=50&s1=%274489212%27.WKU.&OS=PN/4489212&RS=PN/4489212
You can make allyl alcohol from glycerine and oxalic acid (both OTC).
../rhodium/chemistry /allylalcohol.html
I have a book with a process on making allyl alcohol which uses 50 g. of oxalic acid, 200 g. of glycerine and 0.5 g. of ammonium chloride.  No vacuum is used when distilling the formic acid.


http://www.geocities.com/dritte123/PSPF.html
 
 
 
 
    PolytheneSam
(Master Searcher)
08-25-01 13:33
No 207351
      Re: 1,2,4 Trimethoxybenzene  Bookmark   

This looks interesting, too.
Post 205055 (Antoncho: "P2Ps from benzene, acetone and Mn(AcO)3", Novel Discourse)

http://www.geocities.com/dritte123/PSPF.html