obituary (Hive Addict)
08-15-01 18:05
No 204795
      Arom. ald. synth  Bookmark   

Synthesis of Aromatic Aldehydes by means of benzyl halides and sodium salts of nitropropane.
A Hass-Bender Rxn:

ArCH2X +  (CH3)2C=NO2-Na+-(25-80C, abs. EtOH)-> intermediate--> aldehyde (70-80%yeild)

where Ar: just about any sub. you can think of.
     
      X : Br, Cl, I

Hass H. B., Bender M. L., J. Am. Chem.
Soc., 1949, 71, 1767.
Blomquist A. e.a., J. Org. Chem., 1961, 26, 1687.
Klanderman B. H., J. Org. Chem., 1966, 31, 2618.
SOP, 4, 486

http://www.pmf.ukim.edu.mk/PMF/Chemistry/reactions/hass-bender.htm