taranis (Stranger)
08-21-01 09:12
No 206317
      5-meo-dmt  Bookmark   

I have a novel idea on a possable synth for this interesting
tryptamine. i would like any bee's advice.
starting from melatonin with lah reduction to yeild
5-meo-et (ethyl tryptamine) then treated with HNO3 at 0c
and further treated with warm dH2O yeilding 5-meo-hydroxy-t
wich could be put through any of varyos forms of rductive
amination
any input would bee much apreceated.
thnx
 
 
 
 
    taranis
(Stranger)
08-21-01 09:49
No 206322
      Re: 5-meo-dmt  Bookmark   

oops i just found some info on this. but maby it is worth further discution
 
 
 
 
    Lilienthal
(Moderator)
08-21-01 17:44
No 206428
      Re: 5-meo-dmt  Bookmark   

Coool, animated tryptamines... smile
 
 
 
 
    Bwiti
(Hive Addict)
08-24-01 18:15
No 207153
      Re: 5-meo-dmt  Bookmark   

  I would kiss the ground someone walks on if they can find a use for melatonin, because it's cheap. Maybe a reduction with NaBH4, catalyzed by nickel boride would create something worth ingesting? Either way, this is an exciting topic!tongue

  I'm going to help all of you cleanse this diseased planet.
 
 
 
 
    Rhodium
(Chief Bee)
08-25-01 03:51
No 207300
      Re: 5-meo-dmt  Bookmark   

../rhodium/chemistry /mexamine.txt
 
 
 
 
    Bwiti
(Hive Addict)
08-25-01 13:24
No 207350
      Re: 5-meo-dmt  Bookmark   

  Yep, I've seen the mexamine synth, but I don't know if it's active? tongue

  I'm going to help all of you cleanse this diseased planet.
 
 
 
 
    jim
(Hive Bee)
08-25-01 15:26
No 207377
      Re: 5-meo-dmt  Bookmark   

You could try alkylating the mexamine into something more interesting.

Try using MeX and poly(ethylene gylcol) in water, or alcohol.  Or even isopropyl chloride...
 
 
 
 
    taranis
(Stranger)
08-26-01 12:09
No 207555
      Re: 5-meo-dmt  Bookmark   

mexamine is 5-meo-nmt. acording to tihkal it is  as far
as we know not active.
 
 
 
 
    Zen
(Stranger)
01-09-02 23:55
No 254707
      Re: 5-meo-dmt  Bookmark   



"I would kiss the ground someone walks on if they can find a use for melatonin.." -Bwiti



Over here next to me, it's a spot where Shulgin stepped.

Melatonin > 5-Meo-DIPT

-Zen

Ref: Tihkal

"To a solution of 3.0 g 5-methoxytryptamine (see under melatonin for its preparation) in 20 mL sulfolane (tetramethylenesulfone) there was added 8.2 g diisopropylethyl amine and 10.7 g 2-iodopropane, and the two-phase mixture was heated on the steam bath with frequent shaking. After 3 h, the mixture was brought back to room temperature and stirred vigorously for an additional 16 h. After the removal of all volatiles under vacuum, the residue (30 g) was diluted with 100 mL H2O, which gave a clear solution. The addition of 10 mL 5% aqueous NaOH produced a cloudy suspension that was extracted with 3x40 mL hexane. These pooled extracts were stripped of solvent to yield 1.0 g of an almost colorless oil that was distilled at the KugelRohr. A small cut at 100 C (at 0.01 mm / Hg) proved to be largely residual sulfolane (about 0.01 g) and the bulk of the product distilled at 140-150 C to give a viscous white oil, 0.80 g. This was dissolved in 3.5 mL IPA and neutralized with 15 drops of concentrated HCl. The addition of five drops of anhydrous Et2O instigated crystallization, and the product was removed by filtration, washed with 4:1 IPA / Et2O mixture, and air-dried. There was thus obtained 0.85 g of a fine white crystalline product, 5-methoxy-N,N-diisopropyltryptamine hydrochloride (5-MeO-DIPT), with a mp 181-182 C (17%). IR (in cm-1): 731, 809, 826, 931, 1035, 1064, with an NH at 3165. MS (in m/z): C7H16N+ 114 (100%); C4H10N+ 72 (31%); methoxyindolemethylene+ 160 (12%); parent ion 274 (<1%). There was no detectable 5-MeO-NIPT by GC (<1%)."

http://www.erowid.org/library/books_online/tihkal/tihkal37.shtml
 
 
 
 
    Lem2
(Hive Bee)
01-29-02 05:18
No 262282
      Re: 5-meo-dmt  Bookmark   

jim, "Try using MeX and poly(ethylene gylcol) in water, or alcohol." could you please elaborate? Does poly-ethylene glycol stop the formation of the quaternary salt?

He who makes a beast of himself gets rid of the pain of being a man.
 
 
 
 
    cheeseboy
(Hive Bee)
02-05-02 10:42
No 265547
      Re: 5-meo-dmt  Bookmark   

What kind of high does mexamine produce?

May The Source Bee With You....Always.

  - OB1KNoBee
 
 
 
 
    Rhodium
(Chief Bee)
02-05-02 16:26
No 265662
      Re: 5-meo-dmt  Bookmark   

None. It must be dialkylated on the nitrogen first. Mexamine is 5-MeO-Tryptamine.