flipper (Stranger)
08-28-01 00:19
No 207943
      LSD  Bookmark   

I was reading this file about LSD ../rhodium/chemistry/et2lsd.txt
Nice piece of text if you known what HBTU or HATU, HOBt or BOP or HOSu is. Than it would be more understandable.
When its more understandable its easier to win the war. So i'm asking what chemicals these are and what do I suppose to do with them?
 
 
 
 
    Rhodium
(Chief Bee)
08-28-01 03:06
No 207975
      Re: LSD  Bookmark   

The compounds in questions are peptide coupling reagents (compounds which facilitates the reaction between an amine and a carboxylic acid to form and amide, such as Lysergic Acid Diethylamide). More information about them are easily obtainable by searching for them at http://www.google.com
 
 
 
 
    flipper
(Stranger)
08-28-01 07:58
No 208013
      Re: LSD  Bookmark   

HBTU = 2-(1H-benzo-triazole-1-yl)-1,1,3,3-tetramethyluronium
HOBt = N-hydroxybenzotriazole
HOSu = H-Hydroxysuccinimide
BOP  = Benzotriazolyl N-oxytrisdimethylaminophosphonium hexafluorophosphate   
DCC = Dicylohexylcarbodiimide

Still have a question (shame on me)
There were two HBTU s. This one:
2-(1H-benzo-triazol-1-yl)-1,1,3,3-tetramethyluronium Hexafluorophosphate
       
And this one

O-(1H-benzotriazole-1-yl)-N,N,N,n-tetramethyluronium Hexafluorophosphate.

Are these the same?
 
 
 
 
    Lilienthal
(Moderator)
08-28-01 08:12
No 208017
      Re: LSD  Bookmark   

It's the same smile
 
 
 
 
    flipper
(Stranger)
08-28-01 08:49
No 208024
      Re: LSD  Bookmark   

Thanks guys laughsmile
 
 
 
 
    amalgum
(Stranger)
10-06-01 20:24
No 221106
      Re: LSD  Bookmark   

You can get plenty of DCC and HOSu for cheap!
 
 
 
 
    Acme
(Hive Bee)
10-07-01 19:51
No 221477
      Re: LSD  Bookmark   

PyBroP is the shit
 
 
 
 
    amalgum
(Stranger)
10-07-01 23:06
No 221562
      Re: LSD  Bookmark   

These peptide synths look pretty do-able.  Does anybody know if it works?
 
 
 
 
    Rhodium
(Chief Bee)
10-08-01 03:29
No 221612
      Re: LSD  Bookmark   

They work for all other kinds of amide syntheses, so I cannot see why they wouldn't work with LSD.
 
 
 
 
    formula54
(Hive Bee)
11-29-01 09:20
No 242104
      Re: LSD  Bookmark   

heres a great page on coupling reagents
http://www.albmolecular.com/features/tekreps/vol04/no01/v04n01.pdf

-swis54
 
 
 
 
    foxy2
(Distinctive Doe)
11-29-01 09:49
No 242119
      Re: LSD  Bookmark   

Nice Find!!!
Yes Albany Molecular has some fun stuff to browse thru.  I have spent hours there.

Rhodium, this might make your page?
Foxy

Do Your Part To Win The War