IudexK2 (Hive Bee)
10-25-01 19:10
No 228862
      Hexamine for Knoevenagal  Bookmark   

Would hexamine work as a catalyst in the Knoevenagal condensation?

Many thankx,
(Chief Bee)
10-25-01 19:16
No 228864
      Re: Hexamine for Knoevenagal  Bookmark   

Probably not, as the nitroalkane would probably react with the formaldehyde parts of the molecule if the hexamine would hydrolyze. It is also only very weakly basic in its unhydrolyzed form.