timsong (Hive Bee)
11-30-01 15:56
No 242508
      Acetone Enolate via lithium  Bookmark   

Can the sodium metal in the procedure for making Acetone Enolate be substitutes with lithium metal, or will the lithium ethoxide not be strong enough (if there is such a thing as lithium ethoxide ?)
(Chief Bee)
11-30-01 16:25
No 242523
      Re: Acetone Enolate via lithium  Bookmark   

Lithium is okay to use, but it is the anion that is critical. I don't know if ethoxide is a strong enough base, but tert-butoxide certainly is, and perhaps isopropoxide is.