N-Cyclohexylidenethylamine -> PCE , Hive Chemistry Discourse
 
    Bwiti (PVC-Analog Taste-Tester) 12-21-01 21:40 No 249706       N-Cyclohexylidenethylamine -> PCE </td> <td class="text_bg" align="right" valign="top">  <a href="https://www.the-hive.ws/forum/favorites.pl?Cat=&option=add&number=249706&Number=249706&page=82&view=&sort=5&part=&vc=&new=&backto=showflat" title="Add this post to your bookmark list in your Private Area">Bookmark</a>  </td> <td> </td> </tr> <tr class="text_bg"> <td colspan="2" valign="top" align="left"> <br>   Here's a part of the PCE synth from <a href="http://ketamine.net/pcp/imine_synth.html" target="_blank" title="Jump to this external site">http://ketamine.net/pcp/imine_synth.html<wbr></a><br><br>"Next, a solution of phenyllithium was prepared by adding 11 g of lithium metal slowly to 76 ml bromobenzene in 500 ml of ether. This was added dropwise to a solution of 51 g of the N-cyclohexylidenethylamine in 500 ml of ether, with stirring and cooling to keep the temp at 0 deg C. The mixture was heated to reflux with stirring for one hour, and then decomposed by addition of water. The ether layer was separated, washed with water, and extracted into dilute HCl. The acid layers were basified with NaOH and extracted back into organic solvent. The solvent can now be evaporated to yield N-ethyl-1-phenylcyclohexylamine (PCE) freebase."<br><br>  Could phenylmagnesium bromide be used instead? <br><hr>  Love my country. Fear my government. </td> <td> </td> </tr> <tr class="text_bg"> <td align="left" valign="bottom"><img src="../forum/images/left_bottom.gif" border="0" height="12" width="9"></td> <td valign="middle" align="center" colspan="7"> </td> <td align="right" valign="bottom"><img src="../forum/images/right_bottom.gif" border="0" height="12" width="9"></td> </tr> <tr class="page_bg"> <td colspan="9"> </td> </tr> <td align="left" valign="top" class="text_bg"> <img src="../forum/images/left_top.gif" border="0" height="12" width="9"></td> <td colspan="7"><a name="Post249787"></a></a> </td> <td align="right" valign="top"><img src="../forum/images/right_top.gif" border="0" height="12" width="9"></td> </tr> <tr class="text_bg"> <td rowspan="2"> </td> <td rowspan="2"> </td> <td valign="top" align="center" rowspan="2"> Ritter<br> <i>(<span title="The user's title at the time of posting">Master Whacker</span>)</i><br> <span title="Posting date">12-22-01 06:04</span><br> <span title="Link to this post by using the markup [249787]">No 249787</span><br> </td> <td rowspan="2">  </td> <td rowspan="2" width="1" class="vert_ruler"> <img src="../forum/images/hr.gif" border="0" width="1" height="1"> </td> <td rowspan="2">  </td> <td class="text_bg" align="left" valign="top"> <title>Re: N-Cyclohexylidenethylamine -> PCE </td> <td class="text_bg" align="right" valign="top">  <a href="https://www.the-hive.ws/forum/favorites.pl?Cat=&option=add&number=249787&Number=249787&page=82&view=&sort=5&part=&vc=&new=&backto=showflat" title="Add this post to your bookmark list in your Private Area">Bookmark</a>  </td> <td> </td> </tr> <tr class="text_bg"> <td colspan="2" valign="top" align="left"> <br> Absolutely.  Yields should be similar. </td> <td> </td> </tr> <tr class="text_bg"> <td align="left" valign="bottom"><img src="../forum/images/left_bottom.gif" border="0" height="12" width="9"></td> <td valign="middle" align="center" colspan="7"> </td> <td align="right" valign="bottom"><img src="../forum/images/right_bottom.gif" border="0" height="12" width="9"></td> </tr> <tr class="page_bg"> <td colspan="9"> </td> </tr> <td align="left" valign="top" class="text_bg"> <img src="../forum/images/left_top.gif" border="0" height="12" width="9"></td> <td colspan="7"><a name="Post249820"></a></a> </td> <td align="right" valign="top"><img src="../forum/images/right_top.gif" border="0" height="12" width="9"></td> </tr> <tr class="text_bg"> <td rowspan="2"> </td> <td rowspan="2"> </td> <td valign="top" align="center" rowspan="2"> Bwiti<br> <i>(<span title="The user's title at the time of posting">PVC-Analog Taste-Tester</span>)</i><br> <span title="Posting date">12-22-01 08:30</span><br> <span title="Link to this post by using the markup [249820]">No 249820</span><br> </td> <td rowspan="2">  </td> <td rowspan="2" width="1" class="vert_ruler"> <img src="../forum/images/hr.gif" border="0" width="1" height="1"> </td> <td rowspan="2">  </td> <td class="text_bg" align="left" valign="top"> <title>Re: N-Cyclohexylidenethylamine -> PCE </td> <td class="text_bg" align="right" valign="top">  <a href="https://www.the-hive.ws/forum/favorites.pl?Cat=&option=add&number=249820&Number=249820&page=82&view=&sort=5&part=&vc=&new=&backto=showflat" title="Add this post to your bookmark list in your Private Area">Bookmark</a>  </td> <td> </td> </tr> <tr class="text_bg"> <td colspan="2" valign="top" align="left"> <br>   Thanks! As far as making the N-cyclohexylidenethylamine goes, why not say the hell with using p-toluensulfonic acid, bubble the ethylamine into the cyclohexanone and use Mg-sulfate to dry it?<br><hr>  Love my country. Fear my government. </td> <td> </td> </tr> <tr class="text_bg"> <td align="left" valign="bottom"><img src="../forum/images/left_bottom.gif" border="0" height="12" width="9"></td> <td valign="middle" align="center" colspan="7"> </td> <td align="right" valign="bottom"><img src="../forum/images/right_bottom.gif" border="0" height="12" width="9"></td> </tr> <tr class="page_bg"> <td colspan="9"> </td> </tr> <td align="left" valign="top" class="text_bg"> <img src="../forum/images/left_top.gif" border="0" height="12" width="9"></td> <td colspan="7"><a name="Post250333"></a><a name="last"></a></a> </td> <td align="right" valign="top"><img src="../forum/images/right_top.gif" border="0" height="12" width="9"></td> </tr> <tr class="text_bg"> <td rowspan="2"> </td> <td rowspan="2"> </td> <td valign="top" align="center" rowspan="2"> Bwiti<br> <i>(<span title="The user's title at the time of posting">PVC-Analog Taste-Tester</span>)</i><br> <span title="Posting date">12-24-01 22:12</span><br> <span title="Link to this post by using the markup [250333]">No 250333</span><br> </td> <td rowspan="2">  </td> <td rowspan="2" width="1" class="vert_ruler"> <img src="../forum/images/hr.gif" border="0" width="1" height="1"> </td> <td rowspan="2">  </td> <td class="text_bg" align="left" valign="top"> <b title="The subject of this post">Re: N-Cyclohexylidenethylamine -> PCE</b> </td> <td class="text_bg" align="right" valign="top">  <a href="https://www.the-hive.ws/forum/favorites.pl?Cat=&option=add&number=250333&Number=250333&page=82&view=&sort=5&part=&vc=&new=&backto=showflat" title="Add this post to your bookmark list in your Private Area">Bookmark</a>  </td> <td> </td> </tr> <tr class="text_bg"> <td colspan="2" valign="top" align="left"> <br> <font color="blue">"A mixture of 100 g of anhydrous ethylamine and 220 g of cyclohexanone was kept 16 hours, then shaken with solid KOH. The lower oil layer, which comprises the imine ( N-cyclohexylidenethylamine), was then removed by decantation."</font color="blue"> <br>from: <a href="http://chemistry.mdma.ch/hiveboard/rhodium/chemistry /pcp/imine_synth.html" target="_blank" title="Jump to this external site">../rhodium/chemistry /pcp/imi<wbr>ne_synth<wbr>.html</a><br><br>  If the lower oil layer is the imine, then what's the top layer? <br><br><hr>  Love my country. Fear my government. </td> <td> </td> </tr> <tr class="text_bg"> <td align="left" valign="bottom"><img src="../forum/images/left_bottom.gif" border="0" height="12" width="9"></td> <td valign="middle" align="center" colspan="7"> </td> <td align="right" valign="bottom"><img src="../forum/images/right_bottom.gif" border="0" height="12" width="9"></td> </tr> <tr class="page_bg"> <td colspan="9"> </td> </tr> </body> </html>