(Hive Bee)
11-16-02 07:54
No 380235
      salvinorin a / refs from CA 1999-2002
(Rated as: excellent)

naturwissenschaftliche rundschau 2001 54(11): 575-578 (german)
"salvinorin a - a hallucinogen from aztec sage"
heinz benoni

a review. the author reports on the ingredients of salvia divinorum
and its structures, and the effects and mechanisms of action of
salvinorin a.

[chemical abstracts 2002 136: 90781]

forensic sci int 2000 112(2-3): 143-150 (english)
"salvia divinorum: an hallucinogenic mint which might become
a new recreational drug in switzerland"

c. giroud, f. felber, m. augsburger,
b. horisberger, l. rivier, p. mangin

Salvia divinorum is an hallucinogenic mint traditionally used for
curing and divination by the Mazatec Indians of Oaxaca, Mexico. 
Young people from Mexican cities were reported to smoke dried leaves
of S. divinorum as a marijuana substitute. Recently, two S.
divinorum specimens were seized in a large-scale illicit in-door and
out-door hemp plantation.  Salvinorin A also called divinorin A, a
trans-neoclerodane diterpene, was identified in several org. solvent
exts. by gas chromatog.-mass spectrometry.  The botanical identity
of the plant was confirmed by comparing it to an authentic herbarium
specimen.  More plants were then discovered in Swiss horticulturists
greenhouses.  All these data taken together suggest that many
attempts exist in Switzerland to use S. divinorum as a recreational
drug.  This phenomenon may be enhanced because neither the magic
mint, nor its active compd. are banned substances listed in the
Swiss narcotic law.

forensic Salvia salvinorin A drug

Drugs of abuse
Forensic chemistry
Sage (Salvia divinorum)
hallucinogenic mint (Salvia divinorum) as recreational drug
in Switzerland

[chemical abstracts 2001 134: 14085]

phytochem anal 1999 10(1): 22-25 (english)
"high performance liquid chromatographic quantification of
salvinorin a from tissues of salvia divinorum epling & jativa-m"

john w. gruber, daniel j. siebert, ara h.der marderosian,
rick s. hock

A reversed-phase HPLC method for the detn. of salvinorin A, a
psychotropic diterpene isolated from the Mexican sage S. divinorum,
was developed.  Exts. from several plant collections were examd. on
a C-18 column with UV detection and isocratic elution with MeCN-H2O
(45:55).  This assay allowed quantification of salvinorin A in exts.
of leaves and stems of S. divinorum and was also applied to the
screening of related species for the prodn. of salvinorin A.  Levels
of salvinorin A in leaves range from 0.89 to 3.70 mg/g dry wt.

[chemical abstracts 1999 130: 130053]

salvinorin a

CAS [83729-01-5]

(2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-Naphtho[2,1-c]pyran-7-carboxylic acid methyl ester

M( C23H28O8 ) = 432.464 g/mol