slothrop (Newbee)
12-17-02 08:58
No 390260
      Benzyl alcohols to Benzaldehydes  Bookmark   


From Synlett 2002, 12, pp2041-42,
A Novel and Efficient Oxidation of Benzyl Alcohols to Benzaldehydes with DMSO Catalyzed by Acids

Typical procedure: A mixture of 557 mg of benzyl alcohol, 0.15 mL of HBr (48 %) and 5 mL of DMSO was stirred in an oil bath at 100C. TLC (petroleum ether/diethyl ether, 1:1) was used to indicate the completion of the reaction (3 h). To the reaction mixture were added 5 mL brine followed by extraction with 30 mL of diethyl ether. The ether layer was washed with brine (5 mL x 4). Evaporation of the ether and subsequent buld to buld distillation produced 530 mg of benzaldehyde in 95 % yield.

//Tyrone Slothrop
 
 
 
 
    java
(Hive Bee)
12-17-02 13:33
No 390309
      Re: Benzaldehydes  Bookmark   

Good find, ........congratulations!
 
 
 
 
    Rhodium
(Chief Bee)
12-17-02 14:55
No 390326
      Complete article  Bookmark   

../rhodium/chemistry /benzaldehydes.dmso.html
 
 
 
 
    slothrop
(Newbee)
12-17-02 15:06
No 390332
      whoops :-)  Bookmark   

Ops, sorry for being redundant.

//Tyrone Slothrop