Rhodium (Chief Bee)
03-09-03 12:09
No 415098
      PTC Willgerodt synthesis of Phenylacetic Acid  Bookmark   


Phenylacetic acids are efficiently synthesized from acetophenones via thiomorpholides under Phase Transfer Catalytic (PTC) condition. The reaction proceeds efficiently by using triethyl benzyl ammonium chloride (TEBA) as PTC and the reaction time decreased dramatically up to 1/5th to afford pure products in good to excellent yield.

Synthetic Communications 33(1), 59-63 (2003) (../rhodium/chemistry /willgerodt.ptc.html)