(Hive Bee)
06-25-03 12:19
No 442506
      Some recent applications of Amino Nitrile Chemisty
(Rated as: good read)

Some Recent Applications of -Amino Nitrile Chemisty
Chem. Soc. Rev., 29 (5), 359-373 (2000) (


Bifunctional -amino nitriles are not only versatile intermediates in organic synthesis but also exhibit a valuable dual reactivity, which has been utilized in a broad range of synthetic applications. This review highlights recent developments in the chemistry of -amino nitriles, including asymmetric synthesis of -amino acids via Strecker reactions using chiral auxiliaries and catalysts, -amino nitriles as masked iminium ion equivalents in cationic reactions and the synthesis of natural products and heterocycles, and -metallation to provide nucleophilic acyl anion equivalents and applications to asymmetric Umpolung reactions.

We're  all in this world together,
(Chief Bee)
06-25-03 17:08
No 442551
      Amino-nitriles  Bookmark   

Were you thinking of any specific applications of this substance class, or did you just want to share the free review?
(Hive Bee)
06-25-03 19:16
No 442579
      RE:some recent applications of amino Nitrile chem  Bookmark   

In the (Scheme 26 )Summary of reactions of lithiated a-amino nitriles.

Notice that the production of P2P ketone  and diketones in the reaction with lithiated amino nitriles, that cought my eye and could be exploited say using a cheap OTC Phenylalanine  amino

We're  all in this world together,